https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Dysfunction in macula, retinal pigment epithelium and post retinal pathway in acute organophosphorus poisoning https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46395 Wed 28 Jun 2023 15:18:22 AEST ]]> Urinary microRNAs as non-invasive biomarkers for toxic acute kidney injury in humans https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43656 17 fold change (p < 0.0001) and receiver operator characteristics area-under-curve (ROC-AUC) > 0.72. Pathway analysis of target mRNAs of these differentially expressed microRNAs showed association with the regulation of different nephrotoxic signaling pathways. In conclusion, human urinary microRNAs could identify toxic AKI early after acute injury. These urinary microRNAs have potential clinical application as early non-invasive diagnostic AKI biomarkers.]]> Tue 27 Sep 2022 14:32:55 AEST ]]> Prediction of organophosphorus insecticide-induced intermediate syndrome with stimulated concentric needle single fibre electromyography https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33461 33.4µs) within the first 24 hours was associated with greatly increased risk of IMS (odds ratio = 8.9, 95% confidence intervals = 2.4-29.6, p = 0.0003; sensitivity 86%, specificity 58%). The differences in jitter between IMS+ and IMS- patients remained significant for 72 hours and increased jitter was observed in some patients for up to 216 hours. For intubated patients, the median time for jitter to normalize and median time to extubate were similar, and the two variables had a moderate positive correlation (r = 0.49, P = 0.001). Conclusions: Prolonged jitter recorded with SfEMG <24 hours of ingestion of an OP strongly correlates with subsequent occurrence of IMS. The time course of electrophysiological recovery of the NMJ was similar to the time course of respiratory recovery in IMS patients.]]> Tue 03 Sep 2019 18:17:15 AEST ]]> Differences between organophosphates in respiratory failure and lethality with poisoning post the 2011 bans in Sri Lanka https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37250 Thu 10 Nov 2022 11:45:40 AEDT ]]> Serum and urinary biomarkers for early detection of acute kidney injury following Hypnale spp. envenoming https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48602 Mon 01 May 2023 15:45:16 AEST ]]> Early identification of acute kidney injury in Russell's viper (Daboia russelii) envenoming using renal biomarkers https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45713 Fri 04 Nov 2022 10:27:59 AEDT ]]> Changes of attention-related brain activity over 6 months after acute organophosphate pesticide poisoning: a prospective follow-up study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45743 Fri 04 Nov 2022 10:12:56 AEDT ]]>